Molecular Pathways: MERTK Signaling in Cancer

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Molecular pathways: MERTK signaling in cancer.

MERTK is a receptor tyrosine kinase of the TAM (Tyro3, Axl, MERTK) family, with a defined spectrum of normal expression. However, MERTK is overexpressed or ectopically expressed in a wide variety of cancers, including leukemia, non-small cell lung cancer, glioblastoma, melanoma, prostate cancer, breast cancer, colon cancer, gastric cancer, pituitary adenomas, and rhabdomyosarcomas, potentially ...

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Molecular Pathways Molecular Pathways: MERTK Signaling in Cancer

MERTK is a receptor tyrosine kinase of the TAM (Tyro3, Axl, MERTK) family, with a defined spectrum of normal expression. However, MERTK is overexpressed or ectopically expressed in a wide variety of cancers, including leukemia, non–small cell lung cancer, glioblastoma, melanoma, prostate cancer, breast cancer, colon cancer, gastric cancer, pituitary adenomas, and rhabdomyosarcomas, potentially ...

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ژورنال

عنوان ژورنال: Clinical Cancer Research

سال: 2013

ISSN: 1078-0432,1557-3265

DOI: 10.1158/1078-0432.ccr-12-1451